Source – https://www.drugtargetreview.com/ A study has used artificial intelligence to reveal adeno-associated virus (AAV) capsid variants for use in gene therapies. A new study has demonstrated the use of artificial intelligence (AI) to generate a diversity of adeno-associated virus (AAV) capsids towards identifying functional variants capable of evading the immune system, a factor that is critical to Read More
Tag: Gene
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Source – https://www.technologynetworks.com/ In their machine learning-based capsid diversification strategy, the team focused on a 28 amino acid peptide within a segment of the AAV2 VP3 capsid protein that exposes the AAV capsid to neutralizing antibodies produced by individuals and thus can be the cause of an immune response against the virus. More purple colored Read More